Thursday, 14 December, 2017

High doses of vitamin B supplements can cause lung cancer in men

High vitamin B intake increases lung cancer risk among men High doses of vitamin B can raise lung cancer risk for male smokers
Arthur Frazier | 24 August, 2017, 02:51

Among men, taking B6 and B12 from only individual supplement sources was associated with a 30% to 40% increase in risk for lung cancer.

A new study suggests the body's stem cells can soak up unusually high levels of vitamin-C.

Male smokers who consumed the highest levels of vitamin B6 more than tripled their lung cancer risk over six years. The second will examine B6/B12 high dose, long-term supplementation in a second large prospective study of men in an effort to determine whether the increases risk observed in the current study can be replicated.

Brasky said people can easily get enough vitamin B from eating meat, chickpeas and cereal fortified with the vitamin. Male smokers taking B12 at such doses were approximately four times more likely to develop the disease compared to non-users.

For the study, epidemiologists Theodore Brasky (The Ohio State University Comprehensive Cancer Center, Columbia) and colleagues analysed data from the VITamins And Lifestyle (VITAL) cohort study, which was created to assess the use of vitamin and mineral supplements in relation to cancer risk.

The patients, aged 50 to 76, provided detailed information about their vitamin B usage over 10 years, including supplement dosages.

Erdogan urges Turks not to back main German parties
These troops are participating in the US-led coalition's fight against ISIS in Iraq and Syria. There are an estimated three million Turkish-origin people living in Germany.

When Medical News Today spoke with Dr. Brasky, he said, "Unlike most other studies (particularly at the time), we obtained information on supplement frequency of use, duration of use, and dose commonly used in the 10 years prior to the beginning of the study".

Over recent years, a number of studies have looked for links between lung cancer and B vitamins. The team report their findings in Journal of Clinical Oncology. An increased risk of lung cancer was not seen among women or with the vitamin B9, also known as folate.

In a statement, the Council of Responsible Nutrition, a trade association for the dietary supplement industry, said the study doesn't prove that high vitamin B intake causes lung cancer and that the results conflict with other studies measuring vitamin B and lung cancer risk.

"As far as the magnitude of the association, I think you could characterize our reaction as concerned; especially if you consider how common these supplements are".

Why B vitamins influence cancer risk is not known for sure, but some believe that it is related to how B vitamins interact with the so-called one-carbon-metabolism pathway. Notably, smoking seemed to increase the chances of developing the disease significantly more when coupled with vitamin B supplements. In addition to complying with a host of federal and state regulations governing dietary supplements and food in the areas of manufacturing, marketing, quality control and safety, our manufacturer and supplier members also agree to adhere to additional voluntary guidelines as well as to CRN's Code of Ethics.

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